Prevalence, Circulation and Characterization of Multi-resistant Bacteria at Omar Bongo Ondimba Army Instruction Hospital in Libreville
Thiery Ndong Mba
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon and Laboratory of Molecular and cellular Biology, University of Sciences and Technology of Masuku, Franceville, Gabon.
Anita Christel Elvire Mbongo-Kama
Omar Bongo Ondimba Army Instruction Hospital in Libreville, Libreville, Gabon.
Cédric Sima Obiang *
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon.
Rick Léonid Ngoua Meye Misso
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon.
Arnault Mafoumbi
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon and Laboratory of Molecular and cellular Biology, University of Sciences and Technology of Masuku, Franceville, Gabon.
Joseph Privat Ondo
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon.
Louis Clément Obame Engonga
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon.
Patrick Mickala
Laboratory of Molecular and cellular Biology, University of Sciences and Technology of Masuku, Franceville, Gabon.
Edouard Nsi Emvo
Laboratory of Research in Biochemistry, University of Sciences and Technology of Masuku, P.O.Box 913, Franceville, Gabon.
*Author to whom correspondence should be addressed.
Abstract
Multi-resistant bacteria (MRB) pose a global health problem. They lead to increased morbidity, mortality and hospital costs. The main objective of this study is to study the prevalence, circulation and characterization of multi-resistant bacteria.
This is a prospective cross-sectional study of 4 examinations. Bacterial identification was performed using Gram stains, oxidase, catalase, filamentation tests and the Api 20 STAPH, Api 20E systems. The assessment of sensitivity to antibiotics is based on the liquid diffusion method and on the ATB G, ATBTM-EU and ATBTM STAPH galleries previously soaked in antibiotics.
The most common multidrug resistant bacteria were Klebsiella pneumonia, Escherichia coli, Enterobacter cloacae, MRSA and Acinetobacter baumanii. The number of multi-resistant bacteria from cytobacteriological urine examinations was 17, or 43.59% of all isolates. The prevalence of multi-resistant bacteria was 57.14% in blood cultures. In the collection of material from the hospital, the prevalence of multi-resistant strains was 72.73%. The prevalence of multi-resistant strains was 40% in the pus samples.
These results can help define the research perspectives and strategies to be developed to better control the emergence and spread of multi-resistant bacteria in the hospital environment.
Keywords: Prevalence, circulation, multi-resistant bacteria, antibiotics