Risk Factors for Mortality in Hospitalized COVID-19 Patients: A Retrospective Study from the Republic of Guinea
Traore FA *
National Institute of Public Health, Ministry of Health and Public Hygiene, Republic of Guinea and Faculty of health sciences and techniques, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
Kpamy DO
Faculty of health sciences and techniques, Gamal Abdel Nasser University of Conakry, Republic of Guinea and National Health Security Agency, Ministry of Health and Public Hygiene, Republic of Guinea.
Sako FB
Faculty of health sciences and techniques, Gamal Abdel Nasser University of Conakry, Republic of Guinea and National Directorate of Epidemiology and Disease Control, Ministry of Health and Public Hygiene, Republic of Guinea.
Camara G
National Health Security Agency, Ministry of Health and Public Hygiene, Republic of Guinea.
Touré AA
National Institute of Public Health, Ministry of Health and Public Hygiene, Republic of Guinea and Faculty of health sciences and techniques, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
Bah I
Faculty of health sciences and techniques, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
Diallo MOS
Faculty of health sciences and techniques, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
Diare A
National Health Security Agency, Ministry of Health and Public Hygiene, Republic of Guinea.
Kourouma ML
National Health Security Agency, Ministry of Health and Public Hygiene, Republic of Guinea.
Keita I
National Institute of Public Health, Ministry of Health and Public Hygiene, Republic of Guinea.
Doukouré SM
National Health Security Agency, Ministry of Health and Public Hygiene, Republic of Guinea.
*Author to whom correspondence should be addressed.
Abstract
Introduction: The Republic of Guinea, like other countries, has recorded cases of Covid-19 in all its health districts. The aim of this study was to identify the factors associated with death in hospitalised patients.
Methods: This was a retrospective, cross-sectional, analytical study conducted from March 2020 to November 2022, based on records of patients admitted to treatment centres for confirmed Covid-19. Data were collected from 28 out of 38 health districts of the country. A multivariate analysis was used to identify factors associated with risk for mortality.
Results: The study involved 37714 confirmed cases of covid-19. The mean age of the study patients was 37±15 and majority were males (67.34%). Sixty-one percent (61%) had had contact with a covid-19 patient prior to their diagnosis. The mean time to admission to the treatment centre was 2.94 ± 0.01 days. Dyspnea was the most common symptom (76.66%). The most common comorbidities were arterial hypertension (29.41%) and diabetes (22.34%). The average hospital stay was 20 ±0.05 days, with a case fatality rate of 1.23%. The main factors associated with death were age greater than 60 years [OR: 6.29 (95% CI: 4.86-8.15), p=0.000]; hospital stay greater than 2 days [OR: 2.67 (95% CI: 1.6-13.20), p=0.021], diabetes [OR: 2.00 (95% CI: 0.79-4.13), p=0.000]; and arterial hypertension [OR: 9.14 (95% CI: 2.48-9.47), p=0.000]
Conclusion: Taking better account of these factors associated with death, coupled with improving management capacity by raising the level of resuscitation facilities, will help to further reduce Covid-19-related mortality in Guinea.
Keywords: Covid-19, factors, mortality, Guinea, West Africa