Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Meningoencephalitis in an Adult: A Case Report
Abdoul Karim Traoré
*
Department of Anesthesia-Intensive Care-Emergency, Tengandogo University Hospital, Ouagadougou, Burkina Faso.
Hamadé Zonon
Department of Infectious Diseases, Yalgado Ouedraogo University Hospital, Ouagadougou, Burkina Faso.
Moussa Dao
Anesthesia-Intensive Care Unit, Bogodogo University Hospital, Ouagadougou, Burkina Faso.
Ali Soura
Anesthesia-Intensive Care Unit, Yalgado Ouedraogo University Hospital, Ouagadougou, Burkina Faso.
Agnihan Viviane Boni
Department of Infectious Diseases, Sourou Sanou University Hospital, Bobo-Dioulasso, Burkina Faso.
*Author to whom correspondence should be addressed.
Abstract
Meningoencephalitis caused by Extended-spectrum betalactamase (ESBL)-producing E. coli is rare and associated with a high mortality risk, especially if complicated by septic shock. We report the case of a 28-year-old female patient admitted to intensive care unit with febrile coma and meningeal signs, in whom blood cultures and cerebrospinal fluid cultures identified ESBL-producing E. coli. Despite resuscitation measures and broad-spectrum antibiotic therapy, the outcome was unfavourable. This case highlights the diagnostic and therapeutic challenges of such an infection, as well as the need for documentation.
Keywords: Meningoencephalitis, Escherichia coli, ESBL, antimicrobial resistance