Prevalence and Antibiotic-Resistant Pattern of Staphylococcus aureus and Coagulase negative staphylococci Isolated from Wounds among Patients Attending Mogadishu Somali Türkiye Recep Tayyip Erdogan Training and Research Hospital
Omar Sidow Zubair *
Faculty of Medicine, Zamzam University of Science and Technology, Department of Tropical Infectious Disease, Benadir University, Somalia.
Tigaad Abdisad Ali
Infection Prevention Control, Mogadishu Somali Türkiye Recep Tayyip Erdogan Training and Research Hospital, Mogadishu, Somalia.
Abdinasir Khalif
Faculty of Medicine, Zamzam University of Science and Technology, Somalia.
Naima Ali
Faculty of Medicine, Zamzam University of Science and Technology, Somalia.
Ali Kutte Celik
Infectious Disease and Clinical Microbiology, Mogadishu Somali Türkiye Recep Tayyip Erdogan Training and Research Hospital, Somalia.
*Author to whom correspondence should be addressed.
Abstract
Infections caused by Staphylococcus species are frequently linked to wounds, particularly in patients who are hospitalized. Wounds can serve as a source of bacteria that lead to cross-contamination and pose a risk for methicillin-resistant Staphylococcus aureus (MRSA) infections.
Aim: to determine the prevalence and antibiotic Resistance Pattern of staphylococcus species Isolates from Wound infections in a Mogadishu Somali Turk Recep Tayyip Erdogan research and teaching hospital
Patients and Methods: A retrospective cross-sectional study design was used for this study, and 1423 patients diagnosed with wound infection were recruited.
Results: Among the 1,423 individuals surveyed, the overall prevalence of Staphylococcus species isolated was 299 (21%). The prevalence of Staphylococcus aureus was recorded at 16.4%, whereas coagulase-negative staphylococci (CoNS) accounted for 4.6%. Staphylococcus aureus exhibited significant resistance rates to several antibiotics, including Penicillin G (98.7%), Ampicillin (84%), Tetracycline (74%), Erythromycin (73.9%), and Cefoxitin (64%). Conversely, coagulase-negative Staphylococcus showcased high resistance rates to Cefoxitin (66.7%), Erythromycin (70.2%), Ampicillin (85%) and Penicillin G (100%). Notably, both S. aureus and CoNS demonstrated considerable sensitivity to Vancomycin, Linezolid, Daptomycin, and Quinupristin/Dalfopristin.
Conclusion: The study revealed a notable prevalence of Staphylococcus aureus in wound infections, accompanied by significant antibiotic resistance. These findings emphasize the necessity of monitoring resistance patterns to guide treatment strategies effectively. Continued research and surveillance are crucial in the ongoing effort to combat this adaptive pathogen.
Keywords: Staphylococcus aureus, Coagulase negative staphylococcus, drug-resistant, Somalia